Plasmapheresis and CMI Facilities
Apheresis is a medical technology used to extract plasma from the donor’s blood and return the other blood components to the donor’s blood stream. This enables the extraction of a greater quantity of plasma than through the traditional method of whole blood donation, in which blood is collected as one unit and later separated into components.
When making a plasmapheresis donation, the blood flows directly into a sterile single-use kit. Once there, the plasma is separated and extracted while the other blood components—red blood cells and platelets—are returned to the donor’s blood stream. Unlike whole blood donations, donors experience no red cell loss during this process, which reduces the delay between donations from three months to ten days.
When applied to clinical research, apheresis is a powerful technology and can be used to obtain large and frequent samples of plasma for the analysis of relevant fractions like complement, antibodies, etc.
Q&T Research has an apheresis unit with 2 devices, allowing up to 18 procedures per day. For a recent project (NCT02072525) Q&T Research recruited 350 participants over a 9 month period and completed 1050 phasmapheresis procedures over 15 months.
With a dedicated laboratory room, ultra-low freezers, and the expertise of 3 certified CMI technicians, Q&T Research is able to perform PBMC manipulations.
Q&T Research has conducted specialized projects, providing highly specific plasma derivatives, either following vaccinations or with healthy subjects identified with peculiar viral serotypes.